Anne-Claude Leflaive, who presided over one of Burgundy's most storied white wine estates and was a fervent, influential advocate for environmentally sensitive forms of farming, died on Monday at her home in Gilly-lès-Cîteaux, France. She was 59.
She had been ill with cancer for some time, said Jack Daniels, president of Wilson Daniels, her American importer.
Domaine Leflaive, founded by Ms. Leflaive's grandfather, Joseph Leflaive, was already celebrated when she took it over in 1990, in tandem with her cousin, Olivier Leflaive. They had differing visions for the future of the estate, and Olivier left in 1994.
Under Ms. Leflaive's leadership, the reputation of Domaine Leflaive soared, as Burgundy evolved from a connoisseur's passion to a worldwide luxury good. In 2006, Ms. Leflaive was named the best maker of white wines in the world by Decanter magazine.